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Published on: August 14, 2012
Update Regarding Imaging of Neuroendocrine Neoplasms
Jens Holger Figiel1, Simon G Viniol1, Jannis Görlach1
1Diagnostic & Interventional Radiology, University-Hospital of Giessen and Marburg Campus Marburg, Germany.
Background:
Neuroendocrine neoplasms (NEN) are a heterogeneous group of tumors characterized by the expression of typical proteins. A wide range of morphological and functional imaging methods is required in order to adequately assess the course of the disease and to optimally treat the patient. The spectrum of indications ranges from the detection of small primary tumors to the documentation of the metastasis pattern and the assessment of the suitability for certain invasive or noninvasive therapy methods. The exact recording and quantification of findings is indispensable.
Methods:
This article is based on a comprehensive literature search on the different aspects of neuroendocrine neoplasm imaging.
Results:
This article is intended to provide an overview of the available imaging procedures with their respective advantages and disadvantages for diagnostics and their value for the follow-up of neuroendocrine neoplasms. Recommendations for examination protocols, typical image findings, and an outlook regarding future developments are presented.
Key Points:
· Neuroendocrine neoplasms are relatively rare and represent a complex and multiform disease group. Even in metastatic disease, long-term progression-free survival is not uncommon.. · Diagnostics in neuroendocrine neoplasms use a wide range of complementary morphological and functional imaging methods.. · Adequate selection of the imaging method, examination planning and preparation of the patient are essential for exact staging and reliable follow-up..
Citation Format:
· Figiel JH, Viniol SG, Görlach J et al. Update Regarding Imaging of Neuroendocrine Neoplasms. Fortschr Röntgenstr 2020; 192: 171 - 182.
Insights
Accurate imaging is crucial for diagnosing and monitoring neuroendocrine neoplasms (NENs). This review details various imaging techniques, their benefits, and drawbacks for optimal patient management and follow-up.
Area of Science:
- Radiology
- Oncology
- Medical Imaging
Background:
- Neuroendocrine neoplasms (NENs) are rare, complex tumors requiring diverse imaging approaches.
- Accurate assessment of disease course, metastasis, and therapy suitability is vital for NEN patient management.
- Precise recording and quantification of imaging findings are indispensable for effective treatment.
Purpose of the Study:
- To provide a comprehensive overview of imaging procedures for neuroendocrine neoplasms.
- To discuss the advantages and disadvantages of various diagnostic and follow-up imaging methods for NENs.
- To offer recommendations for examination protocols and interpret typical image findings.
Main Methods:
- A comprehensive literature search was conducted on neuroendocrine neoplasm imaging.
- The review synthesizes information on morphological and functional imaging modalities.
- Current literature was analyzed to present an update on NEN imaging.
Main Results:
- Various imaging procedures offer distinct advantages and disadvantages for NEN diagnostics and follow-up.
- Recommendations for optimal examination protocols and typical imaging findings are presented.
- An outlook on future developments in NEN imaging is provided.
Conclusions:
- Neuroendocrine neoplasms are heterogeneous, and long-term survival is possible even with metastatic disease.
- A combination of complementary morphological and functional imaging methods is essential for NEN diagnostics.
- Careful selection of imaging methods, planning, and patient preparation are critical for accurate staging and reliable follow-up.
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