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Updated: Jan 19, 2026

Simultaneous Label-Free Autofluorescence Multi-Harmonic Microscopy
Published on: August 29, 2025
Cascaded harmonic generation from a fiber laser: a milliwatt XUV source
Generating high-order harmonics from Yb-fiber laser harmonics enhances extreme ultraviolet radiation. The third harmonic of the laser optimally drives this process, yielding efficient ultrashort radiation beams.
Area of Science:
- Strong field physics
- Attosecond science
- Laser physics
Background:
- Femtosecond ytterbium-doped fiber lasers offer advancements in strong field physics.
- High-order harmonic generation (HHG) produces high-flux ultrashort extreme ultraviolet (XUV) radiation.
- Optimizing macroscopic parameters is crucial for efficient HHG.
Purpose of the Study:
- Investigate enhancing the single-atom response in HHG.
- Explore HHG driven by multiple harmonics of a femtosecond Yb-fiber laser.
- Determine optimal driving harmonic for efficient XUV generation.
Main Methods:
- Utilized a 50 W, 166 kHz femtosecond Yb-fiber laser system.
- Generated high-order harmonics from the second, third, and fourth harmonics of the fundamental laser output.
- Measured photon flux and average power of generated XUV radiation in argon.
Main Results:
- Harmonic efficiency was found to be optimal when driven by the third harmonic.
- Achieved 6.6 ± 1.3 × 1014 photons/s at 18 eV in argon.
- This corresponds to an average power of 1.9 ± 0.4 mW.
Conclusions:
- The third harmonic of the Yb-fiber laser provides optimal driving conditions for HHG.
- This method enhances the single-atom response for efficient XUV generation.
- Demonstrated a viable pathway for producing high-flux ultrashort XUV radiation.
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