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Updated: Jan 19, 2026

Planar and Three-Dimensional Printing of Conductive Inks
Published on: December 9, 2011
iNK-CD64/16A cells: a promising approach for ADCC?
1Department of Veterinary and Biomedical Sciences, University of Minnesota, St. Paul, MN, USA.
Engineered NK cells expressing a novel high-affinity Fc receptor (CD64/16A) show promise for cancer therapy. This approach enhances antibody-dependent cellular cytotoxicity (ADCC) for improved tumor targeting and overcoming resistance.
Area of Science:
- Immunology
- Cell Therapy
- Oncology
Background:
- Antibody-dependent cellular cytotoxicity (ADCC) mediated by natural killer (NK) cells is crucial for therapeutic antibodies targeting tumors.
- Limited patient responses and resistance to current ADCC therapies are significant challenges.
- NK cells primarily utilize the low-affinity FcγR CD16A for IgG recognition.
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