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Updated: Jan 19, 2026

Behavioral Assessment of Manual Dexterity in Non-Human Primates
Published on: November 11, 2011
Manualized single-session behavior treatment with self-help manual for panic disorder with or without agoraphobia
Titika Mitsopoulou1,2, Yiannis Kasvikis1, Lia Koumantanou1
1Behaviour Therapy Unit, Hellenic Center of Mental Health and Research, Athens, Greece.
Abstract:
Objective: We examined the clinical feasibility and utility of a single behavior treatment session, with 11 patients with Panic Disorder with or without Agoraphobia (PD+/-AG). Patients used an individualized, exposure based, homework manual, derived from their behavioral analysis. Treatment was implemented in an outpatient behavior treatment unit. Method: Patients presented with moderate to severe anxiety, avoidance behavior, functional impairment and depressive symptoms. Treatment was evaluated with a double-baseline case series/pre-post design with four follow-ups. Results: There was a significant and steady improvement in all self-rated outcome measures and participants were satisfied with the services provided. Nine out of 11 patients (82%) were free of PD+/-AG at 3 months and all patients at 1-year follow-up. The absence of a control group, the small sample and lack of blind assessments, limit the validity of the study. Conclusions: These case studies provide empirical evidence in support of both the feasibility and utility of a single-session behavior treatment (SSBT) plus self-help implemented in a public mental health unit. Further research with a control group is needed to assess the efficacy of the intervention in routine clinical practice.
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