Related Experiment Video
Updated: Jan 19, 2026

Author Spotlight: Exploring Photodynamic Therapy with Curcumin in a Murine Model for Oral Candidiasis
Published on: October 27, 2023
Pooled analysis of T2 Candida for rapid diagnosis of candidiasis
Dong-Lan Tang1, Xiao Chen1, Chang-Guo Zhu1
1Department of Clinical Medicine, The Third Clinical School of Guangzhou Medical University, Guangzhou, Guangdong, China.
Background:
The present meta-analysis examined the diagnostic accuracy of T2 Candida for candidiasis.
Methods:
The literature databases, such as PubMed, Embase, DVIO, Cochrane library, Web of Science, and CNKI, were searched on T2 Candida detection.
Results:
A total of 8 articles, comprising of 2717 research subjects, were included in the study. The pooled sensitivity and specificity were 0.91 (95% confidence interval (CI): 0.88-0.94) and 0.94 95% CI: 0.93-0.95), respectively. The pooled positive likelihood ratio and negative likelihood ratio was 10.16 (95% CI: 2.75-37.50) and 0.08 (95% CI: 0.02-0.35), respectively. The combined diagnostic odds ratio is 133.65 95% CI: 17.21-1037.73), and the AUC of SROC is 0.9702 [(SE = 0.0235), Q* = 0.9201(SE = 0.0381)].
Conclusions:
The current evidence supported that T2 Candida has high accuracy and sensitivity and is of major clinical significance in the diagnosis of Candida infection.
Related Concept Videos
06:39Curcuminoid-Mediated Antimicrobial Photodynamic Therapy on a Murine Model of Oral Candidiasis
03:24A Catheter-Related Candida albicans Infection Model in Mouse
06:28Modeling Mucosal Candidiasis in Larval Zebrafish by Swimbladder Injection
08:02Th17 Inflammation Model of Oropharyngeal Candidiasis in Immunodeficient Mice
07:33The Galleria mellonella Waxworm Infection Model for Disseminated Candidiasis
07:57Protocols for Vaginal Inoculation and Sample Collection in the Experimental Mouse Model of Candida vaginitis

