Repeated high blood pressure at 6 and 11 years at the Pelotas 2004 birth cohort study

Marília Cruz Guttier1, Raquel Siqueira Barcelos2, Rodrigo Wiltgen Ferreira3

  • 1Postgraduate Program in Epidemiology, Federal University of Pelotas (UFPel), Cep: 96020-220 - Caixa Postal 464, Rua Marechal Deodoro, 1160 - 3° Piso. Bairro Centro, Pelotas, Rio Grande do Sul, Brazil. maguttier@gmail.com.

BMC Public Health
|September 13, 2019
PubMed

Insights

Repeated high blood pressure in children is linked to maternal gestational diabetes, obesity, family history of hypertension, and prematurity. These factors increase the risk of elevated systolic and diastolic blood pressure over time.

Area of Science:

  • Pediatrics
  • Cardiovascular Health
  • Epidemiology

Background:

  • Study on the prevalence and associated factors of repeated high blood pressure in children.
  • Utilized data from the Pelotas (Brazil) 2004 Birth Cohort.

Purpose of the Study:

  • To evaluate the prevalence of repeated high systolic (SBP) and diastolic blood pressure (DBP).
  • To identify factors associated with persistent elevated blood pressure in children at 6- and 11-year follow-ups.

Main Methods:

  • Enrolled all live births to mothers in Pelotas' urban area.
  • Transformed blood pressure (BP) values into Z-scores by sex, age, and height.
  • Defined high SBP/DBP as repeated BP Z-scores on the ≥95th percentile at two follow-ups; analyzed associations using logistic regression.

Main Results:

  • Prevalence of repeated high SBP was 1.7%, DBP was 2.3%, and both (SDBP) was 1.2%.
  • High SBP associated with males, gestational diabetes mellitus, and childhood obesity.
  • High DBP associated with females, family history of hypertension, and preterm birth (<34 weeks gestation).

Conclusions:

  • Prevalence of repeated high blood pressure was within expected population distributions.
  • Gestational diabetes mellitus, obesity, family history of hypertension, and prematurity are significant risk factors for sustained high blood pressure in children.
  • These findings highlight critical early-life factors influencing long-term cardiovascular health.
Abstract

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