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Related Concept Videos

Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

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The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
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Appendicitis-II: Diagnostic Studies and Management01:29

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Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
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Personal identity is the deeply felt sense of self that individuals cultivate over time, intricately woven from intrinsic qualities they consider essential to their existence—qualities such as morality, intelligence, and friendliness. These attributes serve as vital internal benchmarks, guiding individuals in evaluating whether their actions resonate with their true selves.When personal identity takes center stage in one's life, individuals often emphasize their distinctiveness,...
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Here, we present a protocol for a mosaic labeling technique that permits the visualization of neurons derived from a common progenitor cell in two distinct colors. This facilitates neural lineage analysis with the capability of birth-dating individual neurons and studying gene function in the same neurons of different...
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Related Experiment Video

Updated: Jan 19, 2026

Appendicitis-I: Introduction
01:22

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Simultaneous acute appendicitis in identical twin boys.

Mark L Kovler1, Eric B Jelin1

  • 1Division of General Pediatric Surgery, Johns Hopkins Hospital, Baltimore, Maryland, USA.

BMJ Case Reports
|September 13, 2019
PubMed
Summary

Simultaneous acute appendicitis in identical twin boys suggests a role for both genetic and environmental factors in disease development. This rare case highlights the need for further research into appendicitis etiology.

Keywords:
gastrointestinal surgerypaediatric surgery

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Last Updated: Jan 19, 2026

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Area of Science:

  • Pediatric Surgery
  • Gastroenterology
  • Genetics

Background:

  • Acute appendicitis is a common pediatric abdominal pain cause, yet its etiology remains unclear.
  • Familial aggregation of appendicitis suggests genetic predisposition, but environmental factors are also implicated.

Observation:

  • A rare case of simultaneous acute appendicitis occurred in genetically identical monozygotic twin boys.
  • The twins shared an identical lifestyle, making the simultaneous onset unlikely due to chance alone.

Findings:

  • The simultaneous presentation strongly suggests a combined influence of genetic and environmental factors in acute appendicitis.
  • This case provides compelling evidence for multifactorial etiology in appendicitis.

Implications:

  • Understanding appendicitis in monozygotic twins can aid prompt diagnosis.
  • Further research on appendicitis incidence in twins may clarify predisposing genetic and environmental factors.