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Updated: Jan 19, 2026

Intravital Microscopy of the Microcirculation in the Mouse Cremaster Muscle for the Analysis of Peripheral Stem Cell Migration
Published on: November 5, 2013
Compression bandaging does not compromise peripheral microcirculation in patients with cellulitis of the lower leg
Sophie Bojesen1, Mette Midttun2, Lothar Wiese3
1Department of Internal Medicine, Copenhagen University Hospital, Herlev,, Department of Surgical Gastroenterology, Zealand University Hospital, Køge.
Abstract:
Cellulitis ranks among the most frequent infections, and antibiotic treatment is the accepted mainstay of therapy. There is disagreement on the guidelines for the use of compression bandaging as supplementary treatment, and the evidence within the field is scarce. To determine whether compression bandaging impairs microcirculation in patients with cellulitis of the lower leg, thereby having a negative impact on the supply of oxygen, nutritional components, and antibiotics. Adult patients were prospectively enrolled for compression bandaging in addition to antibiotic treatment. The peripheral blood flow rate was measured before and after application of the compression bandage and on the following day. For this, we applied the heat-washout method, which has previously been shown to provide an accurate estimate of peripheral microcirculation. Comparing the blood flow rate before and after application of the compression bandage showed no significant change and therefore no alteration in microcirculation (p = 0.61). Compression bandaging of the lower leg does not impair microcirculation in patients with cellulitis. This strongly indicates that compression bandaging can play a positive role as supportive treatment in addition to standard antibiotic therapy.
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Muscles that Move the Leg
Anterior Compartment
The quadriceps femoris, the most visible muscle of the anterior compartment, is integral for leg extension and thigh flexion. It is formed by merging four distinct muscles — the vastus lateralis, vastus medialis, vastus intermedius, and rectus femoris. The quadriceps tendon, a shared tendon of the four quadriceps muscles, is affixed...