The Human Chorionic Gonadotropin Derivate EA-230 Modulates the Immune Response and Exerts Renal Protective

Roger van Groenendael1, Remi Beunders2, Matthijs Kox2

  • 1Department of Intensive Care Medicine, Radboud University Medical Center, Nijmegen, the Netherlands; Radboud Institute for Molecular Life Sciences, Radboud Center for Infectious Diseases (RCI), Nijmegen, the Netherlands; Department of Anesthesiology, Pain and Palliative Medicine, Radboud University Medical Center, Nijmegen, the Netherlands; Radboud Institute of Molecular Life Sciences (RIMLS), Nijmegen, the Netherlands.

Seminars in Nephrology
|September 14, 2019
PubMed

Related Concept Videos

Evaluation of Cardiac Contractility Modulation Therapy in 2D Human Stem Cell-Derived Cardiomyocytes08:47

Evaluation of Cardiac Contractility Modulation Therapy in 2D Human Stem Cell-Derived Cardiomyocytes

Here, we demonstrate a non-invasive cardiac medical device contractility evaluation method using 2D human induced pluripotent stem cell-derived cardiomyocyte (hiPSC-CM) monolayers, plated on a flexible substrate, coupled with video-based microscopy. This tool will be useful for the in vitro evaluation of the contractile properties of cardiac electrophysiology...
2.8K
Induction and Assessment of Exertional Skeletal Muscle Damage in Humans08:33

Induction and Assessment of Exertional Skeletal Muscle Damage in Humans

This article describes a safe and reliable method to induce and quantify exertional skeletal muscle damage in human...
7.9K
Xenograft Skin Model to Manipulate Human Immune Responses In Vivo08:23

Xenograft Skin Model to Manipulate Human Immune Responses In Vivo

The present protocol describes how to graft human skin onto non-obese diabetic (NOD)-scid interleukin-2 gamma chain receptor (NSG) mice. A detailed description of the preparation of human skin for transplant, preparation of mice for transplant, transplantation of split-thickness human skin, and post-transplantation recovery procedure are included in the report.
3.7K
A Preclinical Model of Exertional Heat Stroke in Mice08:22

A Preclinical Model of Exertional Heat Stroke in Mice

The protocol describes the development of a standardized, repeatable, preclinical model of exertional heat stroke (EHS) in mice free from adverse external stimuli such as electric shock. The model provides a platform for mechanistic, preventative, and therapeutic...
4.3K
Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice06:32

Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice

We herein detail the methodology followed to compare protective efficacy and lung immune response induced by intranasal and subcutaneous immunization with BCG in mouse model. Our results show the benefits of pulmonary vaccination and suggest a role for IL17-mediated response in vaccine-induced...
11.0K
Transcranial Magnetic Stimulation for Modulating Muscle Response in Humans04:05

Transcranial Magnetic Stimulation for Modulating Muscle Response in Humans

Source: Kuhn, Y. et al. Intracortical Inhibition Within the Primary Motor Cortex Can Be Modulated by Changing the Focus of Attention. J. Vis. Exp. (2017)This video demonstrates the use of transcranial magnetic stimulation (TMS) to modulate motor neuron activity and measure muscle responses via electromyography (EMG). It outlines the steps for locating the motor hotspot, determining stimulation thresholds, and assessing the effects of subthreshold TMS (subTMS) on cortical...
319