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Related Concept Videos

A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy10:02

A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy

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Presented is a concise battery of mouse neonatal motor tests. Using these tests, neonatal motor deficits can be demonstrated in a variety of neonatal motor disorders. By having a standardized set of tests, results from different studies can be compared, allowing for better and accurate reporting between...
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Enhancing the Development and Growth of Infant Cerebral Palsy Rats Using Selective Spinal Manipulations05:04

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This study illustrates the effect of selective spinal manipulation on the growth and development of infant rats with cerebral palsy, emphasizing the specific procedure and standardized protocol. Body weight measurement, Rotarod test, Foot-fault score, other behavioral tests, and growth hormone detection were performed to evaluate the protocol.
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Abdominal Massage to Improve Motor Dysfunction in Rats with Cerebral Palsy08:24

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Here, we present a set of massage manipulations in the rat model of cerebral palsy that can considerably improve the motor function of cerebral palsy...
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Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy08:26

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Several children with unilateral Cerebral Palsy seem to disregard the preserved capacity of their affected upper limb. This Developmental Disregard is extensively described in the literature but the involved cognitive processes have not been studied. To study underlying cognitive factors of upper limb control, an event-related potential protocol was developed.
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Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants11:39

Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants

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We combined frequency-domain near-infrared spectroscopy measures of cerebral hemoglobin oxygenation with diffuse correlation spectroscopy measures of cerebral blood flow index to estimate an index of oxygen metabolism. We tested the utility of this measure as a bedside screening tool to evaluate the health and development of the newborn...
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Calculating Heart Rate Variability from ECG Data from Youth with Cerebral Palsy During Active Video Game Sessions08:12

Calculating Heart Rate Variability from ECG Data from Youth with Cerebral Palsy During Active Video Game Sessions

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This protocol describes a method for calculating Heart Rate Variability (HRV) from electrocardiogram (ECG) waveforms. Waveforms from continuous heart rate (HR) recordings during active video game (AVG) sessions were used to measure the aerobic performance of youth with cerebral palsy...
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Related Experiment Video

Updated: Jan 19, 2026

A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy
10:02

A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy

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Developing a cerebral palsy-specific preference-based measure for a six-dimensional classification system (CP-6D):

Mina Bahrampour1, Richard Norman2, Joshua Byrnes3

  • 1Centre of Applied Health Economics, Griffith University, Menzies Health Institute Queensland, Brisbane, Queensland, Australia mina.bahrampour@griffithuni.edu.au.

BMJ Open
|September 14, 2019
PubMed
Summary

This study developed a new scoring algorithm for the Cerebral Palsy-6 Dimensions (CP-6D) to better measure quality of life for individuals with cerebral palsy (CP). This tool will aid economic evaluations of CP treatments.

Keywords:
Cerebral palsyChoice experimentPreferencehealth related utility values

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Author Spotlight: Exploring the Potential of Massage Therapy in Cerebral Palsy Using Animal Models
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Related Experiment Videos

Last Updated: Jan 19, 2026

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Area of Science:

  • Health Economics
  • Rehabilitation Medicine
  • Quality of Life Research

Background:

  • Cerebral palsy (CP) is a chronic condition impacting quality of life.
  • Existing instruments like CPQOL are disease-specific but don't generate QALYs for cost-utility analysis.
  • Generic utility measures may miss subtle health changes in children with CP.

Purpose of the Study:

  • To develop a preference-based scoring algorithm for the CP-6D classification system.
  • To enable the generation of Quality-Adjusted Life Years (QALYs) for economic evaluations in CP.

Main Methods:

  • A discrete choice experiment with duration (DCEtto) was employed.
  • Health states from the CP-6D were valued by the Australian general population and parents of children with CP via online surveys.
  • Conditional logit regression was used to derive the utility algorithm.

Main Results:

  • A preference-based scoring algorithm for the CP-6D was generated.
  • This algorithm allows for the calculation of QALYs, crucial for cost-utility analyses.

Conclusions:

  • The new CP-6D algorithm enhances economic evaluations of interventions for cerebral palsy.
  • It provides a valuable tool for assessing health-related quality of life and informing treatment decisions in CP.