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Updated: Jan 19, 2026

Laparoscopic Anatomical Liver Segment VII Resection with Liver Parenchymal Transection Following a Priority Approach
Published on: May 23, 2025
Massive Carbon Dioxide Embolism During Laparoscopic Liver Resection: A Case Report
Alessandro De Cassai1, Riccardo Boetto2, Giulia Gabellini3
1Anesthesiology, University of Padova, Padova, ITA.
Massive carbon dioxide embolism during laparoscopic liver surgery is rare but serious. Prompt surgical repair and anesthesiologist cooperation quickly stabilized the patient, preventing long-term consequences.
Area of Science:
- Minimally invasive surgery
- Anesthesiology
- Surgical complications
Background:
- Carbon dioxide embolism (CO2E) is a rare but life-threatening complication during laparoscopic surgery.
- The incidence of CO2E during laparoscopic procedures is low, approximately 0.15%.
- Limited documented evidence exists on the specific effects of massive CO2E during laparoscopic liver resection on critical physiological parameters.
Observation:
- A case of massive CO2 embolism during laparoscopic liver resection is presented.
- The embolism was suspected due to hemodynamic instability and elevated end-tidal CO2 (EtCO2).
- Arterial blood gas analysis confirmed the diagnosis of CO2 embolism.
Findings:
- The patient experienced significant cardiovascular, respiratory, and encephalographic changes due to the massive CO2 embolism.
- Rapid surgical closure of the vascular breach led to immediate improvement in the patient's vital signs.
- No further adverse consequences were observed post-intervention.
Implications:
- This case highlights the critical cardiovascular, respiratory, and encephalographic effects of massive CO2 embolism.
- Emphasizes the necessity of close collaboration between surgeons and anesthesiologists during laparoscopic procedures.
- Underscores the importance of prompt diagnosis and immediate treatment for CO2 embolism to ensure patient safety.
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Carbon Dioxide Transport in the Blood
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1. Dissolved in plasma: A small percentage (7-10%) of CO2 is transported and dissolved directly in the plasma.
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