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Updated: Jan 19, 2026
Visualization of Cortical Modules in Flattened Mammalian Cortices
Published on: January 22, 2018
Accelerated visual recovery from protracted hypoxic cortical blindness in a child
Sasha Mansukhani1, Mai-Lan Ho2,3, Elizabeth A Bradley1
1Departments of Ophthalmology, Mayo Clinic, Rochester, MN, USA.
Purpose:
This report describes accelerated visual recovery in a child following protracted hypoxic cortical visual loss and reviews mechanisms responsible for visual recovery.
Observations:
A 12-year-old boy developed cortical blindness after a severe snowboarding crash. Magnetic resonance imaging showed severe multifocal hypoxic brain injury, with multifocal restricted diffusion and extensive T2/FLAIR hyperintensities throughout the visual cortex, basal ganglia and midbrain. The mismatch of affected areas on FLAIR and DWI sequences indicated a combination of cytotoxic and vasogenic edema, which suggested partial reversibility with potential for recovery. Two weeks after his injury, he began to experience an accelerated improvement in vision with recovery of 20/20 visual acuity and 40 sec/arc stereoacuity over the following week. Three months later, visual field examination showed a steep-margined horizontal band of spared visual field, which showed further expansion on repeat testing 1 year later.
Conclusions And Importance:
Protracted hypoxic cortical visual loss can be followed by dramatic visual recovery in children. Magnetic resonance imaging can provide useful prognostic information.
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