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Updated: Jan 19, 2026

Facile Protocol for the Synthesis of Self-assembling Polyamine-based Peptide Amphiphiles PPAs and Related Biomaterials
Published on: June 25, 2018
Facile synthesis of stable selenocystine peptides and their solution state NMR studies
Ram P Gokula1, Kirti Patel, Shakti K Maurya
1Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai 400076, India. chhbsia@chem.iitb.ac.in.
Abstract:
A facile general route for the synthesis of various selenocystine tripeptides containing acidic, basic and neutral side chain amino acids is reported. Here, TFA labile side chain protected selenocysteine has been used as a precursor for the synthesis of selenopeptides. The peptides are highly stable in dimethyl sulphoxide, thus enabling detailed NMR studies by solution phase 1- and 2-dimensional NMR spectroscopy.
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