Commentary: The future fourth stage of single-ventricle palliation

This video demonstrates the orthotopic transplantation of zebrafish brain tumor cells into the fourth ventricle of an immunocompetent zebrafish embryo. This procedure allows for the long-term study of tumor cell invasion and...

After neural tube formation, the neuroepithelium constricts and folds while the tube fills with embryonic cerebrospinal fluid (eCSF) to form the embryonic brain ventricles. We developed this ventricle injection technique to better visualize the fluid filled space in contrast to the neuroepithelial shape in a live...

The future value (FV) concept is fundamental in finance as it reflects the time value of money. It shows how a current sum of money will grow over time at a specific interest rate. This principle helps investors understand potential investment growth, making it easier to compare different financial options.
Understanding future value offers several benefits. For example, it helps in making informed investment decisions. By projecting investment growth, individuals can compare financial products...

Future value and compounding are essential concepts in finance and critical for understanding the growth of investments over time. The future value (FV) of an investment is the amount that the initial investment, known as the present value (PV), will grow to over a specified period, taking into account the effects of compounding interest. Compounding is the process where the value of an investment grows over time as the earnings from the investment generate additional earnings. This cycle of...

There are hollow fluid-filled cavities known as ventricles deep inside the human brain. There are two lateral ventricles, one in each cerebral hemisphere, and each has three different projections — the anterior, inferior, and posterior horns visible from the lateral side. A thin membrane called the septum pellucidum separates the two lateral ventricles. The slender third ventricle in the diencephalon is connected to each lateral ventricle via a channel called the interventricular foramen.

The present protocol describes a generalized and easy-to-implement scheme for tilted single-particle data collection in cryo-EM experiments. Such a procedure is especially useful for obtaining a high-quality EM map for samples suffering from preferential orientation bias due to adherence to the air-water...