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Updated: Jan 19, 2026

Multi-target Parallel Processing Approach for Gene-to-structure Determination of the Influenza Polymerase PB2 Subunit
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Non-core Subunits of the PRC2 Complex Are Collectively Required for Its Target-Site Specificity

Jonas Westergaard Højfeldt1, Lin Hedehus1, Anne Laugesen1

  • 1Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Copenhagen N 2200, Denmark; The Novo Nordisk Foundation Center for Stem Cell Biology (DanStem), University of Copenhagen, Copenhagen N 2200, Denmark.

Molecular Cell
|September 16, 2019
PubMed
Summary

Non-core subunits of Polycomb repressive complex 2 (PRC2) are crucial for directing its activity. Knocking out these subunits shows they collectively focus H3K27 methylation to specific genomic sites.

Keywords:
EZH2H3K27 methylationH3K27me3PRC1PRC2epigeneticspolycombtranscription

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