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Published on: May 26, 2023
Comparing effectiveness of polydeoxyribonucleotide injection and corticosteroid injection in plantar fasciitis
Dong-Oh Lee1, Jeong-Hyun Yoo1, Hyung-In Cho1
1Department of Orthopedic Surgery, Myongji Hospital, Hanyang University College of Medicine, 697-24 Hwajung-dong, Deokyang-gu, Goyang-si, Gyeonggi-do 10475, Republic of Korea.
Background:
This study aimed to compare the efficacy and safety of polydeoxyribonucleotide (PDRN) injection and corticosteroid injection for plantar fasciitis.
Methods:
This study included 44 patients with plantar fasciitis, randomly allocated to the PDRN and corticosteroid groups. Evaluation using the visual analogue scale (VAS) pain score and Manchester-Oxford foot questionnaire (MOXFQ) was conducted at baseline, 1, 2, 6weeks and 6months. The thickness and echogenicity of the plantar fascia in ultrasonography and complications were recorded.
Results:
Corticosteroid injection elicited more pain relief than did PDRN injection at 2 (p=0.010) and 6weeks (p=0.016); however, it showed no superiority at 6months (p=0.523). MOXFQ showed similar outcomes. The thickness and echogenicity did not differ between groups and no complications were reported in either group.
Conclusions:
We demonstrated that PDRN injection could be an effective and safe option for plantar fasciitis and was comparable to corticosteroid injection after 6months follow up.
Level Of Evidence:
II, comparative study.
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