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Analysis of Liver Microenvironment During Early Progression of Non-Alcoholic Fatty Liver Disease-Associated Hepatocellular Carcinoma in Zebrafish

Here, we present how to generate a non-alcoholic fatty liver disease (NAFLD)-associated Hepatocellular Carcinoma (HCC) zebrafish model to study the impact of cholesterol surplus on liver microenvironment and immune cell...
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Generating Rabbit Liver Carcinoma Model: A Surgical Procedure to Implant Tumor Tissue in Left Lobe of Liver for Induction of Hepatocellular Carcinoma04:34

Generating Rabbit Liver Carcinoma Model: A Surgical Procedure to Implant Tumor Tissue in Left Lobe of Liver for Induction of Hepatocellular Carcinoma

In this video, we demonstrate the surgical implantation of tumor tissue into a rabbit liver to induce hepatocellular carcinoma. The procedure helps establish a reliable animal model to study tumor behavior and development of locoregional treatments targeting cancers of the...
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A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance05:19

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance

Overtreatment is often administered to patients with low-risk prostate cancer; super-active surveillance can help avoid such...
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Evaluation of the Feasibility, Safety, and Accuracy of an Intraoperative High-intensity Focused Ultrasound Device for Treating Liver Metastases05:56

Evaluation of the Feasibility, Safety, and Accuracy of an Intraoperative High-intensity Focused Ultrasound Device for Treating Liver Metastases

Here, we present an ablate-and-resect prospective study to evaluate the feasibility, safety, and accuracy of intraoperative high-intensity focused ultrasound ablation in patients undergoing hepatectomy for liver...
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Assessment of Plasma Coagulation on Liver Tissue in a Large Animal Model In Vivo06:23

Assessment of Plasma Coagulation on Liver Tissue in a Large Animal Model In Vivo

Here we present a protocol to experimentally assess plasma coagulation in liver tissue in vivo. In a porcine model, microcirculation is examined by laser Doppler, coagulation depth is measured histologically, temperature at coagulation site by infrared thermometer and thermographic camera, and duct sealing effect is documented by burst pressure...
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Three-dimensional Location Approach with Silk Thread Guided Laparoscopic Segmentectomy for Liver Tumor06:39

Three-dimensional Location Approach with Silk Thread Guided Laparoscopic Segmentectomy for Liver Tumor

The utilization of 3D reconstruction and virtual simulations in preoperative planning for liver resections represents a significant advancement in surgical oncology. Our team's 3D-LAST (three-dimensional location approach with the silk thread) technique enables safe, efficient, precise tumor removal with practical intraoperative navigation, promising broad medical...
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