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Nanocarriers and Microcarriers for Enhancing the UV Protection of Sunscreens: An Overview
Elisabetta Damiani1, Carmelo Puglia2
1Department of Life and Environmental Sciences, Polytechnic University of the Marche, Ancona, Italy.
Abstract:
This review addresses a major question of importance to pharmaceutical scientists: how can novel drug delivery systems play a role in maximizing the UV protection of sunscreens? Because more and more people are being diagnosed with skin cancer each year than all other cancers combined, adequate sun protective measures are pivotal. In this context, the present review is to give an up-to-date overview on the different nanocarrier systems that have been explored so far for encapsulating different types of UV filters present on the market. The aim of these carrier systems is to prevent skin penetration and to enhance the photoprotective potential of sunscreen actives. For each supramolecular system, a brief description along with the studies, achievements, and pitfalls, on the type of UV actives inside them, ranging from classical UV filters to new generation of UV actives is given. A brief overview of UV filters encapsulated in microcarriers is also discussed.
Insights
Novel nanocarrier systems enhance sunscreen efficacy by encapsulating UV filters. These drug delivery systems aim to maximize UV protection and prevent skin penetration, offering better photoprotection against sun damage.
Area of Science:
- Pharmaceutical Sciences
- Materials Science
- Dermatology
Background:
- Rising skin cancer rates necessitate improved sun protection.
- Sunscreens are crucial for mitigating UV damage.
- Novel drug delivery systems offer advanced solutions for sunscreen formulation.
Purpose of the Study:
- To review nanocarrier systems for UV filter encapsulation in sunscreens.
- To assess the role of these systems in enhancing photoprotection.
- To provide an overview of current research, achievements, and limitations.
Main Methods:
- Literature review of nanocarrier systems for UV filters.
- Analysis of encapsulation strategies for classical and new-generation UV actives.
- Discussion of microcarrier systems for UV filters.
Main Results:
- Nanocarriers effectively encapsulate various UV filters, improving sunscreen performance.
- Encapsulation prevents UV filter skin penetration, enhancing safety.
- Supramolecular systems show promise but have associated challenges.
Conclusions:
- Nanotechnology offers significant potential for advanced sunscreen formulations.
- Drug delivery systems are key to maximizing UV protection and safety.
- Further research into nanocarrier optimization is warranted for effective sun care.
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