Related Experiment Video
Updated: Jan 19, 2026
DC Boost Converters; Testing with Variable Input and Duty Ratio
Published on: April 30, 2023
Sketching neoteric solvents for boosting drugs bioavailability
María S Álvarez1, Yanfei Zhang2
1Department of Chemical Engineering, University of Vigo, P. O. Box 36310, Vigo, Spain; Department of Chemical and Biological Engineering Princeton University, Princeton, NJ, USA.
Deep Eutectic Solvents offer eco-friendly and cost-effective alternatives in pharmaceuticals. These novel solvents, including Therapeutic and Natural Deep Eutectic Solvents, enhance drug solubility and bioavailability for efficient drug delivery systems.
Area of Science:
- Green Chemistry
- Pharmaceutical Science
- Materials Science
Background:
- Neoteric solvents are gaining traction due to cost-effectiveness and reduced environmental impact.
- The pharmaceutical industry seeks greener, non-toxic solvents to improve drug solubility and stability.
- Ionic liquids represent a significant advancement in Green Chemistry, enabling new separation and catalysis.
Purpose of the Study:
- To provide an overview of Deep Eutectic Solvents (DES) as alternatives in pharmaceutical formulations.
- To discuss the advantages and disadvantages of Therapeutic Deep Eutectic Solvents and Natural Deep Eutectic Solvents.
- To explore research directions for developing efficient drug delivery systems using DES.
Main Methods:
- Literature review and synthesis of current research on DES in pharmaceuticals.
- Analysis of the properties and applications of Therapeutic and Natural Deep Eutectic Solvents.
- Discussion of challenges and future perspectives in DES-based drug delivery.
Main Results:
- Deep Eutectic Solvents are attractive due to low-cost raw materials, simple synthesis, and eco-friendly nature.
- Therapeutic and Natural Deep Eutectic Solvents show promise for enhancing drug bioavailability.
- DES offer potential for improved drug solubility and stability in pharmaceutical formulations.
Conclusions:
- Deep Eutectic Solvents present a viable and sustainable option for pharmaceutical applications.
- Further research into DES is crucial for optimizing drug delivery systems and overcoming current limitations.
- The development of efficient drug delivery systems using DES aligns with Green Chemistry principles.
Related Concept Videos
Bioavailability Enhancement: Drug Solubility Enhancement
Bioavailability Enhancement: Drug Permeability Enhancement
DC/DC Boost Converter
Boost converters provide a versatile solution to stepping up DC voltages in many applications where a DC voltage needs to be increased without the need to convert it to AC, using a transformer, and then rectifying the transformer output. Boost converters are step-up converters that use an inductor as an energy storage device that supports the output with additional energy in addition to the DC input...
Solvents
A...
Bioavailability Enhancement: Drug Stability Enhancement and GI Retention
Nonlinear Pharmacokinetics: Bioavailability and Protein-Drug Binding
To quantify the extent of bioavailability, pharmacologists often use a parameter called .