Evaluation of Adjunctive Use of Low-Level Diode Laser Biostimulation with Combined Orthodontic Regenerative Therapy

The combined orthodontic regenerative therapy approach can greatly enhance periodontal conditions and dentofacial aesthetics in many situations. The purpose of this study was to evaluate the effectiveness of 940nm low-level diode laser biostimulation in enhancement of intrabony wound healing with combined orthodontic/regenerative therapy in chronic periodontitis subjects suffering from malocclusion.

Fifteen chronic periodontitis adult patients with at least two intrabony defects and requiring orthodontic treatment for abnormalities in occlusion were included. A total of 30 defects were divided into two groups and treated in a split mouth design. The defects were treated with combined orthodontic regenerative therapy with laser irradiation (Group I: test group) or with combined orthodontic regenerative therapy alone (Group II: control group). The following hard and soft tissue measurements were recorded at baseline (prior to surgery) and after six and nine months postoperatively: probing depth (PD), clinical attachment level (CAL) by periodontal calibrated probe and bone density (BD) using the DBS-Win software.

Probing depth reduction was 64.57%±9.37 and 64.95%±10.07 with no statistically significant difference between Group I and Group II. Percent change in clinical attachment level gain were 59.77%±12.107and 38.83%±7.56 in Group I and II respectively, with a statistically signifi cant difference (P-value =0.005considered signifi cant). Moreover, defects treated with combined orthodontic regenerative therapy with laser irradiation showed signifi cant preservation of bone density with a percent decrease of 4.14%±3.17 at the end of the study period.

Improvements in clinical and radiographic parameters were observed following the adjunctive use of low-level diode laser therapy and orthodontic regenerative therapy for the management of intrabony defects in chronic periodontitis patients.