A New Psychoactive Substance, Gamma Hydroxybutyrate (GHB): A Case Report

Area of Science:

• Neuropharmacology
• Toxicology

Background:

• Gamma Hydroxybutyrate (GHB) is a central nervous system depressant acting on GABA-B receptors.
• GHB is frequently co-ingested with other psychoactive substances like alcohol, cocaine, ecstasy, and amphetamines, particularly in party settings.

Observation:

• GHB use is associated with euphoric effects, reduced anxiety, enhanced communication, increased libido, and altered mental states.
• Acute GHB intoxication presents with symptoms including dizziness, hypotension, bradycardia, nausea, and vomiting.
• Severe adverse events such as epileptic seizures, respiratory depression, and fatalities have been reported with GHB consumption.

Findings:

• The case report details the anamnesis, route of administration, and clinical manifestations of GHB intoxication.
• There is a recognized increase in GHB usage within the country.

Implications:

• Preventative measures should include psycho-education programs and legislative action.
• Incorporating GHB testing into routine substance screening analyses is recommended to monitor and control its use.