Rational MD simulations for improvement the affinity of nanobody against PlGF (placenta growth factor): mutagenesis
Mehdi Forouzesh1, Adil Askerovich Mamedov2, Amirasad Pourabadeh3
1Legal Medicine Organization of Iran, Legal Medicine Research Center, Legal Medicine Organization, Tehran, Iran.
Abstract:
AbbreviationsCOMcenter of mass distanceMDmolecular dynamicsMM-PBSAMolecular Mechanics Poisson-Boltzmann Surface AreaNbnanobodyPlGFplacenta growth factorRgradius of gyrationRMSDroot mean-square deviationSASAsolvent-accessible surface areaVEGFvascular endothelial growth factor.
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