Cerebral venous circulation changes caused by aneurysmal subarachnoid hemorrhage

Area of Science:

• Neurology
• Vascular Medicine
• Radiology

Background:

• Aneurysmal subarachnoid hemorrhage (aSAH) is a severe stroke with high mortality and poor prognosis.
• Understanding cerebral circulation changes is crucial for managing aSAH.

Purpose of the Study:

• To analyze alterations in cerebral venous circulation in aSAH patients using digital subtraction angiography (DSA).
• To compare circulation times between aSAH patients, unruptured aneurysm patients, and controls.

Main Methods:

• Digital subtraction angiography (DSA) was used to analyze cerebral circulation in 57 aSAH patients, 48 unruptured aneurysm patients, and 45 controls.
• Microvascular cerebral circulation time (mCCT) and venous cerebral circulation time (vCCT) were measured.
• Cerebral arterioles and cortical veins were assessed.

Main Results:

• aSAH patients exhibited significantly increased mCCT and vCCT compared to controls (P < 0.05).
• mCCT increased more than vCCT in general aSAH cases (P < 0.001).
• In severe aSAH, vCCT increased more than mCCT (P < 0.01). No significant differences were found between unruptured aneurysm patients and controls.

Conclusions:

• Microvascular cerebral circulation time (mCCT) increases in acute aSAH patients within 72 hours.
• Venous cerebral circulation time (vCCT) shows a greater increase in severe aSAH cases.