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Lipopolysaccharide Infusion as a Porcine Endotoxemic Shock Model05:52

Lipopolysaccharide Infusion as a Porcine Endotoxemic Shock Model

We provide a protocol for an experimental endotoxemic shock model in pigs by infusion of lipopolysaccharide.
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Antibiotic Selection00:57

Antibiotic Selection

Overview
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Characterizing Salmonella Typhimurium-induced Septic Peritonitis in Mice14:10

Characterizing Salmonella Typhimurium-induced Septic Peritonitis in Mice

This protocol describes the induction of Gram-negative monobacterial sepsis in a mouse model system. The model is useful in investigating the inflammatory and lethal host responses during...
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Antibiotic Dereplication Using the Antibiotic Resistance Platform10:49

Antibiotic Dereplication Using the Antibiotic Resistance Platform

We describe a platform that utilizes a library of isogenic antibiotic resistant Escherichia coli for the dereplication of antibiotics. The identity of an antibiotic produced by bacteria or fungi can be deduced by the growth of E. coli expressing its respective resistance gene. This platform is economically effective and...
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Real-Time Monitoring of Neurocritical Patients with Diffuse Optical Spectroscopies07:12

Real-Time Monitoring of Neurocritical Patients with Diffuse Optical Spectroscopies

Presented here is a protocol for non-invasively monitoring cerebral hemodynamics of neurocritical patients in real-time and at the bedside using diffuse optics. Specifically, the proposed protocol uses a hybrid diffuse optical systems to detect and display real-time information on cerebral oxygenation, cerebral blood flow and cerebral...
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Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock09:09

Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock

This article aims to provide researchers with a detailed and accessible guide to set up an infant porcine model of hemorrhagic shock.
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