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Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
Published on: May 23, 2021
First Report of Candida auris Spondylodiscitis in Oman: A Rare Presentation
Sam Supreeth1, Khalifa A Al Ghafri1, Renjit K Jayachandra1
1Khoula Hospital, Muscat, Oman.
Background:
Candida auris is an emerging superbug which was recently discovered and has spread widely across the world. With a steady rise in incidence involving multisystems, this presents a unique challenge to caregivers.
Case Description:
A 50-year-old man with sickle cell disease, diabetes mellitus, and multiple surgeries presented with progressive low back pain radiating to bilateral limbs and intact neurology. Radiologic and laboratory investigations suggested spondylodiscitis with epidural collection, which was operated with posterior decompression and stabilization. The tissue analysis was reported as C. auris, which was accordingly treated with caspofungin. Magnetic resonance imaging at 4 months showed resolution of infection with return of inflammatory markers to normal.
Conclusions:
C. auris appears to be an emerging superbug, which is hospital-acquired. All practitioners must be aware of its existence and presentation. Given the low incidence, high mortality, and no clear guidelines of management so far, formulation of any such strategies is complicated. Further studies and research are needed for this superbug.
Insights
Candida auris, a challenging emerging superbug, can cause severe infections like spondylodiscitis. Early diagnosis and treatment, as seen in this case, are crucial for patient recovery.
Area of Science:
- Infectious Diseases
- Medical Microbiology
- Clinical Case Studies
Background:
- Candida auris is a recently identified, globally spreading multidrug-resistant fungal pathogen.
- Its increasing incidence poses significant challenges in healthcare settings worldwide.
- Candida auris infections can affect multiple organ systems, demanding clinical vigilance.
Observation:
- A 50-year-old male with comorbidities presented with severe low back pain.
- Investigations revealed spondylodiscitis with an epidural collection, suspected to be Candida auris.
- Surgical decompression and stabilization were performed, followed by caspofungin treatment.
Findings:
- Histopathological analysis confirmed Candida auris infection.
- Post-treatment, magnetic resonance imaging at 4 months demonstrated resolution of the infection.
- Inflammatory markers normalized, indicating successful management.
Implications:
- This case highlights Candida auris as a cause of hospital-acquired spondylodiscitis.
- Awareness of its presentation is critical for healthcare practitioners.
- Further research is needed to establish clear management guidelines for this emerging superbug.
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