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Related Experiment Video

Updated: Jan 19, 2026

Palatable Western-style Cafeteria Diet as a Reliable Method for Modeling Diet-induced Obesity in Rodents

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Published on: November 1, 2019

Diet-induced oxalate nephropathy.

Barbara Clark¹, Mohammad Wisam Baqdunes¹, Gregory M Kunkel²

¹Medicine, Allegheny Health Network, Pittsburgh, Pennsylvania, USA.

BMJ Case Reports

|September 19, 2019

Summary

Oxalate nephropathy, a rare kidney disease, can be triggered by high oxalate precursor intake. Early recognition and dietary changes are crucial for managing this condition and preserving kidney function.

Keywords:

acute renal failure nutrition renal system urinary and genital tract disorders

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Last Updated: Jan 19, 2026

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Published on: April 28, 2023

Area of Science:

Nephrology
Toxicology
Internal Medicine

Background:

Oxalate nephropathy is an uncommon cause of kidney injury, often missed due to unrecognized triggers.
Prompt diagnosis and management are essential for preventing irreversible renal damage.

Observation:

An 81-year-old man with well-controlled diabetes presented with gradually increasing creatinine levels.
Acute kidney injury developed, with creatinine rising to 6.8 mg/dL, accompanied by nausea and vomiting.
Urine sediment analysis revealed casts containing calcium oxalate crystals, prompting a detailed dietary history.

Findings:

A comprehensive dietary history revealed significant consumption of oxalate precursors.
Kidney biopsy confirmed the diagnosis of oxalate nephropathy.
Treatment involved oxalate restriction, hydration, and calcium acetate, leading to partial renal recovery.

Implications:

This case highlights the importance of considering oxalate nephropathy in patients with unexplained kidney injury.
Dietary factors, particularly high intake of oxalate precursors, should be thoroughly investigated.
Timely intervention, including dietary modification and medical management, can lead to improved renal outcomes.