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Special Issue "Anticancer Drugs".

Mary J Meegan1, Niamh M O'Boyle2

  • 1School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Trinity Biomedical Sciences Institute, 152-160 Pearse Street, 2 DO2R590 Dublin, Ireland. mmeegan@tcd.ie.

Pharmaceuticals (Basel, Switzerland)
|September 19, 2019
PubMed
Summary

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Correction: Wang et al. Antiproliferative and Tubulin-Destabilising Effects of 3-(Prop-1-en-2-yl)azetidin-2-Ones and Related Compounds in MCF-7 and MDA-MB-231 Breast Cancer Cells. <i>Pharmaceuticals</i> 2023, <i>16</i>, 1000.

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Correction: Malebari et al. Synthesis and Antiproliferative Evaluation of 3-Chloroazetidin-2-ones with Antimitotic Activity: Heterocyclic Bridged Analogues of Combretastatin A-4. <i>Pharmaceuticals</i> 2021, <i>14</i>, 1119.

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Analysis of the structural diversity of heterocycles amongst European medicines agency approved pharmaceuticals (2014-2023).

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This Special Issue explores novel anticancer drugs, focusing on structure-activity relationships and target selection in oncology drug discovery. It covers small molecules and antibody-drug conjugates for improved cancer treatment strategies.

Area of Science:

  • Pharmacology and Medicinal Chemistry
  • Oncology Drug Discovery
  • Molecular Mechanisms of Drug Action

Background:

  • Anticancer drug development requires understanding molecular mechanisms and target selection.
  • Bridging chemical structure with biological activity is crucial for designing effective antitumor agents.
  • Preclinical research encompasses traditional chemotherapeutics, targeted therapies, and biological agents.
Keywords:
cancer drug designcancer immunotherapyconjugate and hybrid drugs, cisplatin resistance, topoisomerase inhibitorsmicrotubule targeted drugssnticancer drugs

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