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Updated: Jan 19, 2026

Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia
Published on: September 22, 2020
Predictive factors for ambulatory state in critical limb ischemia patients at discharge
Shinsuke Imaoka1,2, Koji Sato1, Masahide Hurukawa3
1Department of Rehabilitation, Oita Oka Hospital: 3-7-1 Sakamoto, Nagasaki, Nagasaki 852-8523, Japan.
Abstract:
[Purpose] In patients with critical limb ischemia, the ambulatory state often has a lasting impact on recovery and wound healing. The aim of this study was to examine the predictive factors connected with the ambulatory state in wounds with critical limb ischemia. [Participants and Methods] This study included 125 inpatients with critical limb ischemia, who underwent physical therapy between January 2015 and December 2018. We retrospectively studied factors from the participant's medical records and comparisons were made between the ambulatory and non-ambulatory groups. Next, we analyzed the differences between factors using multiple logistic regression analysis. [Results] The factors associated with the ambulatory state in patients with critical limb ischemia, as determined by multiple logistic regression analysis, were knee extension muscle strength, off-loading the foot duration, and the presence or absence of heart disease. [Conclusion] Shortening off-loading the foot period and intensive rehabilitation at an early stage after amputation need to be prioritized to maintain the quality of life and ambulatory status of patients with wounds in critical limb ischemia.
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