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Induction and Validation of Cellular Senescence in Primary Human Cells
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Age related human T cell subset evolution and senescence

Mingde Li1, Danlin Yao1, Xiangbo Zeng1

  • 11Department of Hematology, First Affiliated Hospital; Institute of Hematology, School of Medicine; Key Laboratory for Regenerative Medicine of Ministry of Education, Jinan University, No.601 West of Huangpu Avenue, Guangzhou, 510632 China.

Immunity & Ageing : I & A
|September 19, 2019
PubMed
Summary

Stem cell memory T cells (TSCM) remain stable with age and gender, suggesting their crucial role in maintaining long-term immunity. Their numbers decrease with age, but their ratio to naive T cells increases, highlighting their importance in aging immunity.

Keywords:
AgeingCentral memory T cellsEffector memory T cellsImmunosenescenceStem cell memory T cell

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