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Updated: Jan 19, 2026

Transarterial Administration of Oncolytic Viruses for Locoregional Therapy of Orthotopic HCC in Rats
Published on: April 15, 2016
Oncolytic Bacteria and their potential role in bacterium-mediated tumour therapy: a conceptual analysis
Yuqing Wang1, Wenxuan Guo1, XiaoLi Wu2
1Institute of Translational Medicine, Nanchang University, Nanchang, Jiangxi 330031, PR China.
Abstract:
As the human microbiota has been confirmed to be of great significance in maintaining health, the dominant bacteria in them have been applied as probiotics to treat various diseases. After the detection of bacteria in tumours, which had previously been considered a sterile region, these bacteria have been isolated and genetically modified for use in tumour therapy. In this review, we sum up the main types of bacteria used in tumour therapy and reveal the mechanisms of both wild type and engineered bacteria in eliminating tumour cells, providing potential possibilities for newly detected, genetically modified, tumour-associated bacteria in anti-tumour therapy.
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