Multiple intrahepatic pancreatic pseudocyst (MIHPPs): an overlooked and misdiagnosed entity

Sagar Tomar1, Rohini Gupta Ghasi1, Juhi Agarwal1

  • 1Department of Radiodiagnosis and Imaging, Safdarjung Hospital, Vardhman Mahavir Medical College, New Delhi, India.

Insights

Multiple intrahepatic pancreatic pseudocysts (MIHPPs) are rare liver lesions. This case highlights MIHPPs presenting as numerous liver cysts without typical pancreatitis signs, a challenging diagnosis.

Area of Science:

  • Gastroenterology
  • Hepatology
  • Radiology

Background:

  • Pancreatitis commonly leads to pseudocysts, typically in the retroperitoneum.
  • Extra-pancreatic pseudocysts, especially within the liver, are rare and often overlooked.
  • Intrahepatic pseudocysts are infrequently reported, usually as solitary or subcapsular lesions.

Observation:

  • This report describes a unique case of multiple intrahepatic pancreatic pseudocysts (MIHPPs).
  • The presentation involved numerous liver cysts without obvious signs of pancreatitis.

Findings:

  • Intrahepatic pancreatic pseudocysts are an underreported entity, with fewer than 50 cases in existing literature.
  • Most reported intrahepatic pseudocysts are subcapsular or solitary, making this case of multiple lesions highly unusual.

Implications:

  • MIHPPs should be considered in the differential diagnosis of complex liver cystic lesions.
  • This highlights the importance of considering extra-pancreatic pseudocysts even in the absence of overt pancreatitis.

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