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Updated: Jan 19, 2026

Robotic Lateral Pancreaticojejunostomy for Chronic Pancreatitis
Published on: December 14, 2019
Multiple intrahepatic pancreatic pseudocyst (MIHPPs): an overlooked and misdiagnosed entity
Sagar Tomar1, Rohini Gupta Ghasi1, Juhi Agarwal1
1Department of Radiodiagnosis and Imaging, Safdarjung Hospital, Vardhman Mahavir Medical College, New Delhi, India.
Abstract:
Pancreatitis and pseudo-pancreatic cysts are frequently encountered entities; however, intrahepatic pseudocysts presenting as large number of liver cysts with absence of overt signs of pancreatitis has never been reported in literature. Here, we report an interesting case of multiple intrahepatic pancreatic pseudocysts (MIHPPs), a challenging diagnosis to be kept in mind while dealing with complex cystic lesions of liver. Pseudocysts are common complication of pancreatitis, often these are located within the vicinity of the pancreas in the lesser sac and the retroperitoneum. Extra pancreatic location of these cysts within the liver is a diagnosis often missed, with only 50 odd cases reported in literature till date. Most of these reported cases are either subcapsular in location or limited in number to one or two lesions. Although rare, possibility of MIHPPs is an important diagnosis that should be kept in mind while considering list of differentials for complex cystic lesions of the liver even in the absence of overt signs of pancreatitis.
Insights
Multiple intrahepatic pancreatic pseudocysts (MIHPPs) are rare liver lesions. This case highlights MIHPPs presenting as numerous liver cysts without typical pancreatitis signs, a challenging diagnosis.
Area of Science:
- Gastroenterology
- Hepatology
- Radiology
Background:
- Pancreatitis commonly leads to pseudocysts, typically in the retroperitoneum.
- Extra-pancreatic pseudocysts, especially within the liver, are rare and often overlooked.
- Intrahepatic pseudocysts are infrequently reported, usually as solitary or subcapsular lesions.
Observation:
- This report describes a unique case of multiple intrahepatic pancreatic pseudocysts (MIHPPs).
- The presentation involved numerous liver cysts without obvious signs of pancreatitis.
Findings:
- Intrahepatic pancreatic pseudocysts are an underreported entity, with fewer than 50 cases in existing literature.
- Most reported intrahepatic pseudocysts are subcapsular or solitary, making this case of multiple lesions highly unusual.
Implications:
- MIHPPs should be considered in the differential diagnosis of complex liver cystic lesions.
- This highlights the importance of considering extra-pancreatic pseudocysts even in the absence of overt pancreatitis.
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