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Updated: Jan 19, 2026

A "Patient-Like" Orthotopic Syngeneic Mouse Model of Hepatocellular Carcinoma Metastasis
Published on: October 24, 2015
Brain metastasis from urachal carcinoma
Kento Takahara1, Yoichi Mochizuki1, Shinya Ichimura1
1Department of Neurosurgery, Shizuoka City Shimizu Hospital, Shizuoka.
Urachal carcinoma (UC) brain metastasis is rare. Surgical tumor removal is the preferred treatment, with local radiotherapy as a viable option over whole brain radiotherapy.
Area of Science:
- Oncology
- Neurosurgery
- Pathology
Background:
- Urachal carcinoma (UC) is an uncommon bladder cancer variant.
- Brain metastasis from UC is exceptionally rare, with limited documented cases.
Observation:
- A case of a 77-year-old female with urachal adenocarcinoma metastasis to the cerebellum is presented.
- The metastasis was surgically removed and pathologically confirmed.
- Recurrence was observed and treated with gamma knife radiotherapy.
Findings:
- Surgical resection of brain metastasis from urachal carcinoma is the primary treatment of choice.
- Local radiotherapy, including gamma knife, is a suitable alternative to routine whole brain radiotherapy for recurrences.
Implications:
- This case contributes to the limited literature on urachal carcinoma brain metastasis.
- Highlights the efficacy of surgical management and targeted radiotherapy for this rare condition.
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