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Updated: Jan 19, 2026
Endocarditis II: Clinical Features of Infective Endocarditis
Published on: June 19, 2025
Infective endocarditis: a consumptive disease among the elderly
Vilma Takayasu1, Fabiana Roberto Lima2, Fernando Peixoto Ferraz de Campos1
1Department of Internal Medicine - Hospital Universitário, Universidade de São Paulo, São Paulo/SP - Brazil.
Infective endocarditis in elderly patients can present subtly, mimicking other conditions like cancer. Prompt diagnosis is crucial, as delayed treatment can lead to severe complications.
Area of Science:
- Cardiology
- Infectious Diseases
- Geriatrics
Background:
- Infective endocarditis (IE) diagnosis in elderly patients presents unique challenges due to atypical presentations.
- Subacute IE often has an indolent course, with slow development of cardiac lesions.
- Anemia and weight loss can be prominent symptoms, potentially masking the true diagnosis.
Observation:
- A case of an elderly patient with degenerative mitral valve disease is presented.
- The patient developed bacterial endocarditis caused by Streptococcus mitis.
- Clinical presentation included significant weight loss and absence of fever, leading to diagnostic delays.
Findings:
- The patient's endocarditis was not treated due to a delayed diagnosis.
- Autopsy revealed mitral valve and left atrium impairment from endocarditis.
- Lung involvement was noted, potentially linked to biomass fuel smoke inhalation.
Implications:
- Highlights the importance of considering IE in elderly patients with non-specific symptoms like weight loss and no fever.
- Emphasizes the need for timely diagnostic evaluation to prevent severe outcomes.
- Suggests potential environmental factors, such as biomass smoke, may influence respiratory health in conjunction with IE.
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