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Multimodal imaging in posterior microphthalmos.

Reza Karkhaneh1, Ahmad Masoumi1, Nazanin Ebrahimiadib1

  • 1Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Journal of Current Ophthalmology
|September 19, 2019
PubMed
Summary
This summary is machine-generated.

Optical coherence tomography angiography (OCTA) revealed an absent foveal avascular zone in posterior microphthalmos (PM) patients. Optical coherence tomography (OCT) also showed retinal folds and retinoschisis, highlighting key imaging findings in this condition.

Keywords:
MaculaOptical coherence tomography angiographyPosterior microphthalmosRetinal fold

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Area of Science:

  • Ophthalmology
  • Medical Imaging

Background:

  • Posterior microphthalmos (PM) is a rare congenital condition characterized by a small eye with a normal or near-normal anterior segment.
  • Multimodal imaging plays a crucial role in understanding the complex ocular abnormalities associated with PM.

Purpose of the Study:

  • To evaluate the utility of multimodal imaging, specifically optical coherence tomography angiography (OCTA), in characterizing posterior microphthalmos (PM).
  • To document the OCTA and optical coherence tomography (OCT) findings in patients diagnosed with PM.

Main Methods:

  • An observational case series included two patients (four eyes) with clinically diagnosed PM.
  • Comprehensive ophthalmic examinations were performed, including fluorescein angiography, OCT, OCTA, B-scan ultrasonography, axial length measurement, and Pentacam evaluation.

Main Results:

  • Patients presented with high hyperopia, macular retinal folds, retinoschisis, and foveal hypoplasia.
  • OCTA demonstrated an absence of the foveal avascular zone (FAZ) in both superficial and deep capillary plexuses.
  • Pentacam revealed corneal steepness, shallow anterior chambers, and reduced anterior chamber volumes.

Conclusions:

  • OCTA is valuable for visualizing vascular anomalies in PM, showing an absent FAZ.
  • OCT imaging identified structural abnormalities like retinal folds and retinoschisis.
  • Multimodal imaging provides a comprehensive understanding of the ocular characteristics in posterior microphthalmos.