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Updated: Jan 19, 2026
DNA Virus Detection System Based on RPA-CRISPR/Cas12a-SPM and Deep Learning
Published on: May 10, 2024
DeepMSPeptide: peptide detectability prediction using deep learning
Guillermo Serrano1, Elizabeth Guruceaga1,2, Victor Segura1,2
1Bioinformatics Platform, Center for Applied Medical Research, University of Navarra, Pamplona 31008, Spain.
Summary:
The protein detection and quantification using high-throughput proteomic technologies is still challenging due to the stochastic nature of the peptide selection in the mass spectrometer, the difficulties in the statistical analysis of the results and the presence of degenerated peptides. However, considering in the analysis only those peptides that could be detected by mass spectrometry, also called proteotypic peptides, increases the accuracy of the results. Several approaches have been applied to predict peptide detectability based on the physicochemical properties of the peptides. In this manuscript, we present DeepMSPeptide, a bioinformatic tool that uses a deep learning method to predict proteotypic peptides exclusively based on the peptide amino acid sequences.
Availability And Implementation:
DeepMSPeptide is available at https://github.com/vsegurar/DeepMSPeptide.
Supplementary Information:
Supplementary data are available at Bioinformatics online.
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