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Reduction in morphological sickling of red cells incubated with quinine
1Department of Pediatrics, University of South Alabama College of Medicine, Mobile 36617.
Pediatric Hematology and Oncology
|January 1, 1987
Abstract:
Quinine HCl reduced the formation of reversibly sickled cells in vitro over a concentration range of 0.2-5.0 mM. Quinidine and chloroquine had similar effects. Combinations of quinine and cyanate demonstrated synergistic, antisickling properties in vitro.