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Related Experiment Video

Updated: Jan 19, 2026

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Optic nerve head microvascular changes after phacoemulsification surgery.

Müjdat Karabulut1, Sinem Karabulut2, Sabahattin Sül2

  • 1Department of Ophthalmology, Mugla Sıtkı Koçman University Medical School, Mugla, Turkey. mujdatkarabulut@gmail.com.

Graefe'S Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie
|September 19, 2019
PubMed
Summary

Phacoemulsification surgery may decrease intraocular pressure (IOP) and increase optic nerve head (ONH) microvasculature. This study observed significant changes in vessel density (VD) and IOP four weeks post-surgery.

Keywords:
Intraocular pressure phacoemulsificationOptical coherence tomography angiographyVessel density

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Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Vascular Biology

Background:

  • Phacoemulsification surgery is a common procedure for cataracts.
  • Microvascular changes in the optic nerve head (ONH) and intraocular pressure (IOP) are critical in ocular health.
  • Optical coherence tomography angiography (OCTA) allows for detailed imaging of ONH vasculature.

Purpose of the Study:

  • To investigate microvascular changes in the ONH using OCTA.
  • To assess changes in IOP following uncomplicated phacoemulsification surgery.
  • To determine the correlation between ONH microvascular changes and IOP fluctuations post-surgery.

Main Methods:

  • Prospective observational study including 24 eyes.
  • Exclusion criteria: retinal vascular pathology, AMD, IOP > 21 mmHg, abnormal axial length, corneal edema, and prior ocular surgery.
  • OCTA imaging and IOP measurements were taken preoperatively and at 1 and 4 weeks postoperatively.

Main Results:

  • Vessel density (VD) significantly increased in all ONH quadrants by week 4 compared to week 1.
  • Significant differences in VD and IOP were observed at week 4 compared to baseline (p<0.05 and p<0.001).
  • IOP was significantly lower at week 4 (14.8 mmHg) versus week 1 (16.0 mmHg) (p<0.001), with a negative correlation between ONH VD and IOP.

Conclusions:

  • Uncomplicated phacoemulsification surgery can lead to a reduction in IOP.
  • The procedure may also result in an increase in the vessel density of the optic nerve head.
  • These findings suggest a potential impact of cataract surgery on ocular hemodynamics.