Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Lessons learned from the Japanese nephritis screening study.

T Kitagawa1

  • 1Department of Pediatrics, School of Medicine, Nihon University, Tokyo, Japan.

Pediatric Nephrology (Berlin, Germany)
|April 1, 1988
PubMed
Summary

Japan's 13-year school urine screening program successfully detected early-stage kidney diseases like IgA nephropathy. This early detection of asymptomatic renal disease aids in understanding disease epidemiology and facilitates timely management.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clonal growth of hepatitis B virus-integrated hepatocytes in cirrhotic liver nodules.

Cancer research·1992
Same author

Intraarterial lymphocyte-injection therapy for lymphedema of the leg: an examination using indium-111 oxine labeled autologous lymphocytes.

The Tokushima journal of experimental medicine·1992
Same author

[A case report of Lucas-Schmidt IIA type Cor triatriatum in neonate].

[Zasshi] [Journal]. Nihon Kyobu Geka Gakkai·1992
Same author

Capillary gas chromatographic method for the determination of the thromboxane A2 receptor antagonist S-1452 and its metabolites in human plasma.

Journal of chromatography·1992
Same author

Capillary gas chromatographic method for the determination of the thromboxane A2 receptor antagonist S-1452 and its metabolites in human urine.

Journal of chromatography·1992
Same author

[MR angiography of the lung using 3-dimensional imaging method].

Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica·1992

Area of Science:

  • Nephrology
  • Pediatric Medicine
  • Public Health

Background:

  • A long-standing urine screening program for school children in Japan has aimed for early detection of asymptomatic renal disease.
  • Understanding the epidemiological impact of this nationwide screening on chronic glomerular diseases is crucial.

Purpose of the Study:

  • To assess the contribution of a 13-year nationwide school urine screening program to understanding the epidemiology of chronic glomerular disease in Japan.
  • To evaluate the detection rates of specific glomerulonephritis types through mass urine screening.

Main Methods:

  • A multicenter survey of patients identified through the school urine screening program.
  • Analysis of detection rates for IgA nephropathy, non-IgA mesangial proliferative glomerulonephritis, and membranous proliferative glomerulonephritis (MPGN).

Related Experiment Videos

Main Results:

  • Mass urine screening detected 70-80% of IgA and non-IgA mesangial proliferative glomerulonephritis cases and 65-80% of MPGN cases.
  • Severe glomerular lesions were more common in children with incidental proteinuria/hematuria and significant proteinuria.
  • Mild glomerular changes were frequent in MPGN and mesangial proliferative nephritis detected via screening, often with minimal proteinuria.

Conclusions:

  • The Japanese school urine screening program is effective in the early detection of various chronic glomerular diseases.
  • Screening identifies patients with milder disease presentations, suggesting potential for early intervention and management.
  • Early detection through screening may facilitate timely management of glomerular diseases, particularly when effective treatments are available.