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Haemolytic uraemic syndrome associated with faecal cytotoxin and verotoxin neutralizing antibodies
A A Novillo1, L E Voyer, R Cravioto
1Department of Virology and Bacteriology, Instituto Nacional de Microbiología Carlos G. Malbrán, Buenos Aires, Argentina.
Pediatric Nephrology (Berlin, Germany)
|July 1, 1988
Abstract:
Forty-nine patients with a diagnosis of idiopathic haemolytic uraemic syndrome (HUS) were investigated to determine evidence of infection by verotoxin-producing Escherichia coli (VTEC). Free faecal cytotoxin active on Vero cells (VT) was detected in 15 out of 49 patients (31%). Seroconversion or high titres of VT-neutralizing antibodies were detected in 11 out of 18 patients (61%). The results of the present study suggest an association between HUS and infection by VTEC.