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Related Concept Videos

Translation01:31

Translation

155.6K
Lesson: Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of...
155.6K
Translation01:31

Translation

17.5K
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Proteins are...
17.5K
Initiation of Translation02:33

Initiation of Translation

38.4K
Initiating translation is complex because it involves multiple molecules. Initiator tRNA, ribosomal subunits, and eukaryotic initiation factors (eIFs) are all required to assemble on the initiation codon of mRNA. This process consists of several steps that are mediated by different eIFs.
First, the initiator tRNA must be selected from the pool of elongator tRNAs by eukaryotic initiation factor 2 (eIF2). The initiator tRNA (Met-tRNAi) has conserved sequence elements including modified bases at...
38.4K
Termination of Translation01:44

Termination of Translation

27.4K
The large ribosomal subunit has several important structures essential to translation. These include the peptidyl transferase center (PTC) - which is the site where the peptide bond is formed - and a large, internal, water-filled tube through which the nascent polypeptide moves. This latter structure is called the Peptide Exit Tunnel, and it begins at the PTC and spans the body of the large ribosomal subunit. During translation, as the nascent polypeptide chain is synthesized, it passes through...
27.4K
Making Patch-pipettes and Sharp Electrodes with a Programmable Puller05:30

Making Patch-pipettes and Sharp Electrodes with a Programmable Puller

25.9K
This video shows how to use a programmable puller to make patch pipettes and sharp electrodes for electrophysiology. The same procedure can be used to make a variety of glass tools, including injection...
25.9K
Hierarchical and Programmable One-Pot Oligosaccharide Synthesis09:56

Hierarchical and Programmable One-Pot Oligosaccharide Synthesis

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This protocol demonstrates how to use the Auto-CHO software for hierarchical and programmable one-pot synthesis of oligosaccharides. It also describes the general procedure for RRV determination experiments and one-pot glycosylation of...
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Related Experiment Video

Updated: Jan 19, 2026

Making Patch-pipettes and Sharp Electrodes with a Programmable Puller
05:30

Making Patch-pipettes and Sharp Electrodes with a Programmable Puller

Published on: October 8, 2008

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From country control programmes to translational research.

Lydia Leonardo1, Robert Bergquist2, Remigio Olveda3

  • 1Institute of Biology, College of Science, University of the Philippines Diliman and University of the East Ramon Magsaysay Graduate School, Quezon City, Philippines.

Advances in Parasitology
|September 19, 2019
PubMed
Summary

RNA interference (RNAi) research focuses on disease control and prevention, developing advanced diagnostics and surveillance tools. Adapting strategies to local contexts and evaluating program success are crucial for disease elimination.

Keywords:
ClonorchiasisDiagnosticsLymphatic filariasisMolluscicideOpisthorchiasisRNAS(+)Schistosomiasis surveillanceTranslational research

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A Simple Approach to Perform TEER Measurements Using a Self-Made Volt-Amperemeter with Programmable Output Frequency
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A Simple Approach to Perform TEER Measurements Using a Self-Made Volt-Amperemeter with Programmable Output Frequency

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Area of Science:

  • * Public Health
  • * Tropical Medicine
  • * Epidemiology

Background:

  • * RNAS+ has focused on research for disease control, prevention, and elimination since 1998.
  • * Diagnostics development is crucial for all stages of disease control, from initial efforts to transmission blocking.
  • * Chemotherapy is effective for schistosomiasis morbidity, but improved diagnostics and vaccines are needed.

Purpose of the Study:

  • * To review research advancements and program evaluations for disease control and elimination.
  • * To highlight the importance of surveillance, risk mapping, and adaptive control strategies.
  • * To present new management models and success stories, including disease elimination.

Main Methods:

  • * Review of research and program implementation reports.
  • * Development of spatio-temporal tools and ecological models using Geographical Information Systems (GIS).
  • * Determination of disability weights and updating epidemiological profiles.

Main Results:

  • * Enhanced diagnostics and vaccine research complement chemotherapy for diseases like schistosomiasis.
  • * GIS-based risk maps are essential for surveillance in low-prevalence areas.
  • * Program evaluations revealed challenges in chemotherapy distribution and socio-cultural factors, emphasizing the need for adapted control activities.

Conclusions:

  • * Integrating advanced diagnostics, surveillance, and adaptive strategies is key to disease control and elimination.
  • * Understanding social, cultural, and behavioral aspects is vital for effective public health interventions.
  • * Success stories like lymphatic filariasis elimination demonstrate the impact of tailored control programs.