Childhood renal disorders in Saudi Arabia

M B Abdurrahman1, A T Elidrissy

  • 1Department of Paediatrics, College of Medicine, Riyadh, Saudia Arabia.

Insights

Childhood renal disorders in Saudi Arabia show unique patterns, with hereditary conditions and kidney stones being common. Preventable causes of kidney failure in children include reflux nephropathy and posterior urethral valves.

Area of Science:

  • Pediatrics
  • Nephrology
  • Epidemiology

Background:

  • Childhood renal disorders present unique challenges in Saudi Arabia.
  • Understanding local patterns is crucial for effective management and public health strategies.

Purpose of the Study:

  • To provide an overview of childhood renal disorders in Saudi Arabia.
  • To compare the local disease pattern with global trends.

Main Methods:

  • Retrospective analysis of patient data from a large teaching hospital in Saudi Arabia.
  • Characterization of the frequency and types of renal diseases in children.

Main Results:

  • Heredofamilial disorders and renal calculi are common in Saudi children.
  • Mesangioproliferative glomerulonephritis is a frequent cause of non-minimal change nephrotic syndrome.
  • Reflux nephropathy and posterior urethral valves are identified as preventable causes of end-stage renal failure.

Conclusions:

  • The pattern of childhood renal disorders in Saudi Arabia shares similarities with global data but exhibits distinct frequencies.
  • Early identification and intervention for conditions like reflux nephropathy are vital to prevent progression to end-stage renal failure.

Related Concept Videos

Disorders of the Urinary System01:20

Disorders of the Urinary System

The urinary system is responsible for eliminating waste and excess fluids from the body. However, disorders of the urinary system can arise due to various reasons like infections, stress, age, congenital abnormalities, and lifestyle.
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...