Bilateral Sterile Pyogranulomatous Keratitis in a Dog

Area of Science:

• Veterinary Ophthalmology
• Canine Pathology

Background:

• Bilateral sterile pyogranulomatous keratitis is a severe inflammatory eye condition.
• This case involves a 16-year-old rat terrier with progressive corneal plaques.

Observation:

• The dog presented with corneal ulceration that healed, followed by plaque development.
• Over one year, plaques covered both corneas, leading to blindness and pain.

Findings:

• Histopathology confirmed bilateral pyogranulomatous keratitis.
• No causative organisms were identified, indicating a sterile inflammatory process.

Implications:

• This is the first documented case of bilateral sterile pyogranulomatous keratitis in a dog.
• Highlights the need for further research into the etiology and treatment of this condition.