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The Iridovirus frog virus 3: a model for trans-acting proteins
1Department of Virology and Molecular Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.
Abstract:
The amphibian Iridovirus, frog virus 3 (FV3), produces at least two trans-activating proteins that stimulate the expression of viral genes. One of these proteins induces transcription from the promoter of an immediate-early FV3 gene, whereas the other induces transcription from exogenously methylated DNA. These proteins may serve as a model for both viral and cellular trans-acting factors.