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Hepatitis B virus proteins eliciting protective immunity
A R Neurath1, B A Jameson, T Huima
1New York Blood Center, New York 100021.
Abstract:
The immune response to current hepatitis B vaccines appears to be qualitatively different from the response elicited during recovery from natural infection. Such disparate responses can probably be explained by the absence or under-representation of preS- and the nucleoprotein core-specific determinants in the vaccines. The incorporation of these determinants into future vaccines may improve their efficacy.