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Related Concept Videos

Using the Activity-based Anorexia Rodent Model to Study the Neurobiological Basis of Anorexia Nervosa07:46

Using the Activity-based Anorexia Rodent Model to Study the Neurobiological Basis of Anorexia Nervosa

15.1K
Here we present a protocol to induce activity-based anorexia (ABA) in female adolescent mice. ABA is a condition of hyperactivity evoked by imposing food restriction on rodents with access to a running wheel. This phenomenon is being used as a model to study the underlying neurobiology of anorexia nervosa.
15.1K
Anorexia Nervosa01:28

Anorexia Nervosa

1.0K
Anorexia nervosa is a complex and severe eating disorder characterized by an intense fear of weight gain, an unrelenting pursuit of thinness, and a distorted body image. It often leads to dangerously low body weight relative to an individual's age and height. This disorder is marked by significant physical and psychological consequences, making it one of the most life-threatening psychiatric illnesses.
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
1.0K
Assessing Activity-based Anorexia in Mice08:26

Assessing Activity-based Anorexia in Mice

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Mice individually housed with a running wheel while given limited access to food develop reductions in food consumption and increase activity on the running wheel. This experimental phenomenon is called activity-based anorexia. This paradigm provides an experimental tool for studying the neurobiology and behaviors underlying aspects of anorexia...
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Bulimia Nervosa01:30

Bulimia Nervosa

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Bulimia nervosa is a complex and severe eating disorder characterized by a cyclical pattern of binge-and-purge eating pattern. It generally involves an episode of binge eating, followed by compensatory behaviors such as vomiting, excessive exercise, laxative use, or fasting, to prevent weight gain. Despite often maintaining a normal weight, individuals with bulimia are intensely preoccupied with their body image and harbor an overwhelming fear of gaining weight. This can contribute to the...
701
Data Reporting and Recording01:24

Data Reporting and Recording

5.3K
Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
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Types of Reports I: Hands-off Report01:25

Types of Reports I: Hands-off Report

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A hand-off report, also known as a change-of-shift report, is a crucial nursing process that ensures the smooth transition of patient care responsibilities between nursing staff.
Following are the key components and categories of hand-off reports:
Purpose and Process:
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Related Experiment Video

Updated: Jan 19, 2026

Using the Activity-based Anorexia Rodent Model to Study the Neurobiological Basis of Anorexia Nervosa
07:46

Using the Activity-based Anorexia Rodent Model to Study the Neurobiological Basis of Anorexia Nervosa

Published on: October 22, 2015

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Pellagra and anorexia nervosa: a case report.

Sandra Portale1, Michele Sculati2, Fatima Cody Stanford3,4

  • 1Laboratory of Dietetics and Clinical Nutrition, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Via Bassi 21, 27100, Pavia, PV, Italy. sandra.portale@gmail.com.

Eating and Weight Disorders : EWD
|September 19, 2019
PubMed
Summary

Pellagra, a niacin deficiency disease, can occur even without severe malnutrition. Early recognition and treatment with nicotinamide are crucial, especially in patients with eating disorders like anorexia nervosa.

Keywords:
Anorexia nervosaCase reportNiacin deficiencyPellagra

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Anorexia Nervosa
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Assessing Activity-based Anorexia in Mice
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Related Experiment Videos

Last Updated: Jan 19, 2026

Using the Activity-based Anorexia Rodent Model to Study the Neurobiological Basis of Anorexia Nervosa
07:46

Using the Activity-based Anorexia Rodent Model to Study the Neurobiological Basis of Anorexia Nervosa

Published on: October 22, 2015

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Anorexia Nervosa
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Anorexia Nervosa

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Assessing Activity-based Anorexia in Mice
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Area of Science:

  • Nutritional Biochemistry
  • Clinical Medicine
  • Dermatology

Background:

  • Pellagra, a disease caused by niacin deficiency, is currently considered rare but remains a potential clinical diagnosis.
  • Recognizing pellagra's diverse manifestations is essential for prompt and effective patient management.

Observation:

  • A case study of a 28-year-old woman with anorexia nervosa presented with classic pellagra symptoms: erythema, diarrhea, and neurological deficits.
  • The patient, despite not showing signs of severe underweight or malnutrition, was diagnosed with pellagra.

Findings:

  • Diagnosis was established clinically, and the patient experienced a swift recovery following treatment with nicotinamide and tryptophan.
  • This case highlights that pellagra can manifest atypically, even in the absence of pronounced malnutrition.

Implications:

  • Clinicians should maintain a high index of suspicion for pellagra in patients with a history of eating disorders.
  • This case underscores the importance of considering pellagra in the differential diagnosis of unexplained dermatological, gastrointestinal, and neurological symptoms.