[The clinical significance of bacteria Acinetobacter spp., separated from patients with chronic osteomyelitis.]

The article deals with the results of analysis of 17 clinical strains of Acinetobacter spp., isolated from wounds of patients with chronic osteomyelitis of long bones. In 8 patients strains of Acinetobacter spp. were isolated in mono-culture, in 8 - in composition of association with staphylococci (Staphylococcus aureus - 4, S.epidermidis - 2, S.hatmolyticus - 1, S.capitis -1) and in one patient - with strains of Enteroccocus faecalis. highly adhesive characteristics were established in 29% of isolates of Acinetobacter spp, average adhesive - in 43% and low adhesive - in 28%. The average index of adhesiveness of analyzed strains made up to 2.86±0.02 units. The strains with high adhesive potential were isolated from associations with Staphylococcus spp. The strains of Acinebacter spp. are characterized as far as of incubating by increasing activity of formation of biofilm on the surface of 96 alveolar tray. The calculated integral coefficient (K>0.5 units) testifies high percentage of strains resistant to selected antibiotics. It is established that the most effective in relation to Acinebacter spp. were aminoglycosides (gentamycin and tobramycin) and carbapenems (meropenem, imipenem).The percentage of resistant strains did not exceed 38%. The implemented study demonstrated that inter-microbial relationships ameliorate capacity of association-forming strains Acinebacter spp. to form bio-films. The derived values of bio-film-forming capacity and coefficient of resistance of clinical isolates Acinebacter spp.isolated from patients with chronic osteomyelitis testify their high pathogenicity. The treatment of infection associated with Acinebacter spp. is to consider both results of antibioticgram and data concerning virulent characteristics of isolated agent.