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A Model for Epilepsy of Infectious Etiology using Theiler's Murine Encephalomyelitis Virus
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Infectious Myelitis

Archana Asundi1,2, Anna M Cervantes-Arslanian1,2,3, Nina H Lin1,2

  • 1Division of Infectious Diseases, Boston Medical Center, Boston, Massachusetts.

Seminars in Neurology
|September 19, 2019
PubMed

Insights

This review details infectious myelitis, spinal cord inflammation caused by pathogens. It provides clinicians with diagnostic and treatment strategies for viral, bacterial, parasitic, and fungal causes.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Pathology

Background:

  • Myelitis is spinal cord inflammation potentially causing neurological deficits.
  • Infectious agents are a key cause, acting directly or via immune responses.
  • This review focuses on direct pathogenic effects causing myelitis.

Purpose of the Study:

  • To summarize clinical manifestations of infectious myelitis.
  • To provide a diagnostic workup for suspected cases.
  • To outline key pathogens, their presentations, diagnostics, and treatments.

Main Methods:

  • Literature review of infectious myelitis.
  • Synthesis of information on clinical presentations.
  • Compilation of diagnostic and treatment guidelines.

Main Results:

  • Infectious myelitis presents with diverse neurological impairments.
  • Diagnostic approaches involve identifying specific pathogens.
  • Viral, bacterial, parasitic, and fungal agents are significant causes.

Conclusions:

  • Prompt recognition and diagnosis of infectious myelitis are crucial.
  • Understanding pathogen-specific features aids clinical management.
  • Effective treatment strategies depend on accurate etiologic diagnosis.

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