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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
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Concomitant Interstitial Lung Disease with Psoriasis.

Genta Ishikawa1, Sakshi Dua1, Aditi Mathur1

  • 1Division of Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Canadian Respiratory Journal
|September 20, 2019
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Summary
This summary is machine-generated.

This case series examined patients with psoriasis and interstitial lung disease (ILD). Psoriasis and ILD co-occurred in 4.7% of patients, highlighting a potential association requiring further study.

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Area of Science:

  • Pulmonology
  • Dermatology
  • Rheumatology

Background:

  • Psoriasis is a chronic inflammatory condition.
  • Interstitial lung disease (ILD) encompasses a group of lung disorders.
  • Concomitant occurrence of psoriasis and ILD is observed in clinical practice.

Purpose of the Study:

  • To investigate the clinical and radiographic features of patients diagnosed with both psoriasis and ILD.
  • To identify characteristics of individuals with coexisting psoriasis and interstitial lung disease.

Main Methods:

  • Retrospective review of a dedicated institutional database for Interstitial Lung Disease (ILD).
  • Identification of patients with a history of or concurrent diagnosis of psoriasis among 447 ILD cases.
  • Abstraction of clinical, radiographic, pathological, and outcome data from medical records.

Main Results:

  • 21 patients (4.7%) had concomitant or antecedent psoriasis diagnoses.
  • The median age was 66 years, with 66.7% being male.
  • Common ILD diagnoses included idiopathic pulmonary fibrosis (52.4%) and usual interstitial pneumonia pattern (42.9%) on imaging.

Conclusions:

  • This study identified 21 cases of interstitial lung disease (ILD) in patients with psoriasis.
  • Further prospective research is needed to elucidate the relationship between ILD and psoriasis.