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Outcome Of Percutaneous Nephrolithotomy In Preschool And School-Age Children-Single Center Experience
Nadeem Iqbal1, Aisha Hasan1, Fasih Sami Siddiqui1
1Department of Urology, Shifa International hospital Islamabad, Pakistan.
Insights
Percutaneous nephrolithotomy (PCNL) is safe and effective for pediatric kidney stones in both preschool and school-aged children. Stone-free rates and complications were similar across both age groups.
Area of Science:
- Pediatric Urology
- Nephrolithiasis Management
- Minimally Invasive Surgery
Background:
- Percutaneous nephrolithotomy (PCNL) efficacy is well-established in adults but less studied in children.
- Pediatric PCNL adoption is increasing for various age groups.
- Limited data exists on PCNL safety and efficacy in distinct pediatric age cohorts.
Purpose of the Study:
- To evaluate the safety and efficacy of PCNL in two pediatric age groups: preschool (≤7 years) and school-age (≥7 years).
- To compare stone-free rates and complication profiles between these pediatric age groups.
Main Methods:
- Retrospective review of 59 pediatric patients undergoing PCNL from December 2009 to May 2017.
- Patients categorized into two groups: preschool (n=27, mean age 4.8±2.1 years) and school-age (n=32, mean age 11.8±4.6 years).
- Analysis of stone size, operative time, hospital stay, stone clearance, and complications.
Main Results:
- Mean stone size (309±55 mm² vs 324±63 mm²) and operative time (150.1±38.7 min vs 166.3±39.6 min) were comparable between preschool and school-age groups.
- Mean hospital stay was similar (3.1±1.4 days vs 2.9±1.3 days).
- Monotherapy stone clearance was high in both groups (96.3% preschool, 93.75% school-age), reaching 100% with adjunctive extracorporeal shock wave lithotripsy.
Conclusions:
- PCNL demonstrates equal effectiveness in achieving stone-free rates for both preschool and school-age pediatric patients.
- Complication rates were not significantly different between the two age groups, indicating comparable safety profiles.
Background:
Efficacy of percutaneous nephrolithotomy in adults has been studied well in past. However, such studies are sparse within paediatric age group. As this procedure is being adopted in smaller and older children alike, we wanted to determine its safety and efficacy in two different age groups of children (preschool age and school age).
Methods:
The records of 59 children undergoing PCNL at our department from December 2009 to May 2017 were reviewed retrospectively. Patients were placed into 2 age groups including children ≤7 years old (group 1) and those ≥7 years (group 2). Twenty-seven patients were put in preschool group with mean age of 4.8±2.1 years while 32 patients in school age group having mean age of 11.8±4.6 years.
Results:
Stone size was calculated showing mean 309±55 mm2 in preschool and 324±63 mm2 in school age group respectively (p=0.1). The mean operative time was 150.1±38.7 minutes and 166.3±39.6 minutes in the preschool and school age children respectively (p=0.1). The mean length of hospital stay was 3.1±1.4 days and 2.9±1.3 days in preschool and school going children (p=0.5). The stone clearance with PCNL was seen in 96.3% (pre-school group) and 93.75% (school age group) as monotherapy (p=0.1), which increased to 100% after combining it with extracorporeal shock wave lithotripsy.
Conclusions:
PCNL is equally effective in both pre-school and school age groups in terms of stone free rates. Complication rates were not different between the two groups.
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