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Simple and robust polymer-based sensor for rapid cancer detection using serum
Ngoc D B Le1, Arvind K Singla2, Yingying Geng1
1Department of Chemistry, University of Massachusetts Amherst, 710 N. Pleasant St., Amherst, MA 01003, USA. rotello@chem.umass.edu.
Chemical Communications (Cambridge, England)
|September 20, 2019
Abstract:
We report a polymer-based sensor that rapidly detects cancer based on changes in serum protein levels. Using three ratiometric fluorescence outputs, this simple system identifies early stage and metastatic lung cancer with a high level of accuracy exceeding many biomarker-based assays, making it an attractive strategy for point-of-care testing.
